http://www.erictdawson.com/series/graph-genomes/Recent content in Graph Genomes on Dr. Eric T. DawsonHugoenSat, 01 Apr 2017 00:00:00 +0000http://www.erictdawson.com/posts/sv-genotyping-vg-v1/Sat, 01 Apr 2017 00:00:00 +0000http://www.erictdawson.com/posts/sv-genotyping-vg-v1/<p>This past year I&rsquo;ve been working with the <a href="https://github.com/vgteam" class="external-link" target="_blank" rel="noopener">vgteam</a> on the variation graph toolkit, or vg. vg has grown nicely into a very functional software package for graph construction, read mapping, SNP/MNP calling, and visualization.</p> <p>I&rsquo;ve been working on methods for detecting structural variants using the graph, both novel SVs in the sample being analyzed and shared SVs known to exist in a population. I&rsquo;m certainly not the only one, and at least two other variant callers exist in vg already. Currently I&rsquo;m testing a method for genotyping known indels of any size, but I&rsquo;d like to extend this to other, more complex forms of structural variation as well as novel variant detection.</p>